B-Raf IN 11 (ZINC72115182) 是一种选择性的B-RafV600E抑制剂 (IC50=76 nM),其对 B-RafV600E的选择性高于 B-RafWT,选择性为 3.1 倍,可用于结直肠癌的研究。
生物活性 | B-Raf IN 11 (ZINC72115182) is a selectiveB-RafV600Einhibitor (IC50=76 nM), shows selectivity for
B-RafV600Eover B-RafWTwith selectivity of 3.1-fold. B-Raf IN 11 can be used in colorectalcancerresearch[1] |
IC50& Target[1] | B-RafV600E 76 nM (IC50) | BRAFWT 238 nM (IC50) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Powder | -20°C | 3 years | | 4°C | 2 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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