CAS NO: | 228113-66-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | Maralixibat (SHP625) chloride is an orally activeileal bile acid transporter (IBAT)inhibitor. Maralixibat chloride can be used for the treatment of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC) and biliary atresia[1][2]. | ||||||||||||||||
体内研究 (In Vivo) | Maralixibat chloride reduces elevations in sBA levels, improves liver function, and reduces liver tissue damage, in a rat partial bile duct ligation model of cholestasis[2]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 710.41 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C40H56ClN3O4S | ||||||||||||||||
CAS 号 | 228113-66-4 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 50 mg/mL(70.38 mM;ultrasonic and warming and heat to 60℃) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |