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IDH1 Inhibitor 3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
IDH1 Inhibitor 3图片
CAS NO:2171081-24-4
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
IDH1 Inhibitor 3 (compound 6f) 是突变型的 IDH1 的抑制剂，其对IDH1R132H 的 IC50 值为 45 nM。
Cas No.2171081-24-4
Canonical SMILESO=C([C@@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@]3(C(NC4CC(F)(F)C4)=O)CCC5=C3C=CC=C5)C6=CC(F)=CC(F)=C6
分子式C31H25F4N5O3
分子量591.56
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1]. IC50: 45 nM (IDH1R132H)[1].

[1]. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.