CRM1 degrader 1 (1l) 是一种低毒的染色体区域维护 1 (CRM1) 降解剂。CRM1 是几种肿瘤抑制因子的唯一核输出蛋白,这是一种生长调节蛋白,是一种有吸引力的癌症药物靶点。CRM1 degrader 1 诱导胃癌凋亡 (Apoptosis) 并选择性抑制胃癌的增殖。
生物活性 | CRM1degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader.CRM1is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractivecancerdrug target.CRM1degrader 1 induces theapoptosisin gastric carcinoma and selectively inhibits proliferation of gastriccancer[1]. |
分子量 | |
Formula | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |