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DGAT1-IN-1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
DGAT1-IN-1图片
CAS NO:1449779-49-0
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
2mg电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
DGAT1-IN-1是高效DGAT1抑制剂，IC50值低于10nM（Hep3B细胞过表达DGAT1裂解物测得）。
Cas No.1449779-49-0
Canonical SMILESOC(C[C@H]1CC[C@H](C2=CC=C(C3=CN4C=C(C(NCC5=CC=C(OC(F)(F)F)C=C5)=O)N=C4C=C3)C=C2)CC1)=O
分子式C30H28F3N3O4
分子量551.56
溶解度DMSO: 20 mg/mL (36.26 mM); Water:< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of< 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).IC50 value:< 10 nMTarget: DGAT1 inhibitorImidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparationBy Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.

[1]. Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme , Patent: WO 2013119040 A1