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5'-Guanylic acid disodium salt
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
5'-Guanylic acid disodium salt图片
CAS NO:5550-12-9
包装与价格：
包装价格(元)
Free Sample (0.1-0.5mg)电议
100mg电议
200mg电议
500mg电议

产品介绍
5'-Guanylic acid disodium salt (5'-GMP disodium salt) 是由鸟嘌呤，核糖和磷酸部分组成，是一种信使 RNA 中的核苷酸单体。 鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
Cas No.5550-12-9
别名5'-鸟苷酸二钠
Canonical SMILESO=P([O-])(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=C(N)NC3=O)O1)O)O)[O-].[Na+].[Na+]
分子式C10H12N5Na2O8P
分子量407.18
溶解度Water: 100 mg/mL (245.59 mM); DMSO:< 1 mg/mL (insoluble or slightly soluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes[1]. Human Endogenous Metabolite

[1]. Lan T, et al. Type II cGMP-dependent protein kinase phosphorylates EGFR at threonine 669 and thereby inhibits its activation. Biochem Biophys Res Commun. 2019 Aug 6.