13-Hydroxyisobakuchiol

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

178765-49-6

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
25mg	电议

产品名称

Delta3,2-Hydroxylbakuchiol

产品介绍

13-Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol) 是从Psoralea corylifolia中分离得到，Bakuchiol (HY-N0235) 的类似物。13-Hydroxyisobakuchiol 是一种有效的单胺转运蛋白 (monoamine transporter) 抑制剂，它对多巴胺转运蛋白 (DAT) (IC₅₀=0.58 μM) 和去甲肾上腺素转运蛋白 (NET) (IC₅₀=0.69 μM) 的选择性比血清素转运蛋白 (SERT) (IC₅₀=312.02 μM) 更强。13-Hydroxyisobakuchiol 有潜力用于帕金森病、抑郁症和可卡因成瘾等疾病的研究。

生物活性	Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated fromPsoralea corylifolia(L.), is a potentmonoamine transporterinhibitor. 13-Hydroxyisobakuchiol is more selective for thedopamine transporter(DAT) (IC₅₀=0.58 μM) and norepinephrine transporter (NET) (IC₅₀=0.69 μM) than for theserotonin transporter(SERT) (IC₅₀=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction^[1].
IC₅₀& Target	IC50: 0.58 μM (dopamine transporter) IC50: 0.69 μM (norepinephrine transporter)^[1]
分子量	272.38
Formula	C₁₈H₂₄O₂
CAS 号	178765-49-6
结构分类	Phenols Monophenols
来源	Plants Leguminosae Psoralea corylifoliaL.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.