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13-Hydroxyisobakuchiol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
13-Hydroxyisobakuchiol图片
CAS NO:178765-49-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
Delta3,2-Hydroxylbakuchiol
产品介绍
13-Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol) 是从Psoralea corylifolia中分离得到,Bakuchiol (HY-N0235) 的类似物。13-Hydroxyisobakuchiol 是一种有效的单胺转运蛋白 (monoamine transporter) 抑制剂,它对多巴胺转运蛋白 (DAT) (IC50=0.58 μM) 和去甲肾上腺素转运蛋白 (NET) (IC50=0.69 μM) 的选择性比血清素转运蛋白 (SERT) (IC50=312.02 μM) 更强。13-Hydroxyisobakuchiol 有潜力用于帕金森病、抑郁症和可卡因成瘾等疾病的研究。
生物活性

Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated fromPsoralea corylifolia(L.), is a potentmonoamine transporterinhibitor. 13-Hydroxyisobakuchiol is more selective for thedopamine transporter(DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for theserotonin transporter(SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction[1].

IC50& Target

IC50: 0.58 μM (dopamine transporter)
IC50: 0.69 μM (norepinephrine transporter)[1]

分子量

272.38

Formula

C18H24O2

CAS 号

178765-49-6

结构分类
  • Phenols
  • Monophenols
来源
  • Plants
  • Leguminosae
  • Psoralea corylifoliaL.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.