Valbenazine tosylate (NBI-98854 tosylate) is a vesicularmonoamine transporter2 (VMAT2) inhibitor with theK_iof 110-190 nM^[1].

Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with K_is of 110 and 150 nM, respectively^[1].

Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response in rats^[1].

762.97

C₃₈H₅₄N₂O₁₀S₂

1639208-54-0

Room temperature in continental US; may vary elsewhere.

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