| CAS NO: | 187870-95-7 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 生物活性 | Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of theNa+/H+exchanger (NHE-1). |
| IC50& Target | NHE1[1] |
| 体外研究 (In Vitro) | Blocking NHE-1 activity has been shown to decrease intracellular Na+and Ca2+overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1]. |
| Clinical Trial | |
| 分子量 | 369.84 |
| Formula | C11H16ClN3O5S2 |
| CAS 号 | 187870-95-7 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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