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Juglone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Juglone图片
CAS NO:481-39-0
包装与价格:
包装价格(元)
500mg电议
1g电议

产品介绍
Juglone 是一种在黑胡桃 (Juglans regia) 中发现的黄色色素。
Cas No.481-39-0
别名胡桃醌; 5-Hydroxy-1,4-naphthalenedione
Canonical SMILESO=C1C=CC(C2=CC=CC(O)=C21)=O
分子式C10H6O3
分子量174.2
溶解度DMSO: 10 mg/ml,Ethanol: 10 mg/ml
储存条件4°C, protect from light ,unstable in solution, ready to use.
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. It has allelopathic actions, suppressing growth, photosynthesis, and respiration in plants and other organisms, although some bacteria can metabolize juglone. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 µM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.