您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Acivicin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Acivicin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Acivicin图片
CAS NO:42228-92-2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Acivicin (AT-125) 是一种由 Streptomyces sviceus 生产的天然产物,是一种 γ-谷氨酰转肽酶 (GGT) 抑制剂。
Cas No.42228-92-2
别名异恶唑醋酸
Canonical SMILESClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1
分子式C5H7ClN2O3
分子量178.6
溶解度PBS (pH 7.2): 1.4 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively). It also reversibly inhibits γ-glutamyl transpeptidase. Acividin has been used to elucidate aspects of glutathione metabolism and has known anti-tumorigenic activity.