3-O-Methyltolcapone-d4 (Ro 40-7591-d4) is the deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potentCOMTinhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

291.29

C₁₅H₉D₄NO₅

2469274-07-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.