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AKT Kinase Inhibitor hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AKT Kinase Inhibitor hydrochloride图片
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
AKT Kinase Inhibitor hydrochloride 是一种具有抗肿瘤活性的Akt抑制剂。
生物活性

AKTKinase Inhibitor hydrochloride is anAktkinase inhibitor with anti-tumor activity[1].

体外研究
(In Vitro)

The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion[1].

体内研究
(In Vivo)

Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus[1].

分子量

393.83

性状

Solid

Formula

C16H20ClN7O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)