包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Disitertide (P144) diammonium is a peptidictransforming growth factor-beta 1 (TGF-β1)inhibitor specifically designed to block the interaction with its receptor. Disitertide diammonium is also aPI3Kinhibitor and anapoptosisinducer[1][2][3][4][5]. | ||||||||||||||||
体外研究 (In Vitro) | Disitertide (P144, 100 μg/mL) diammonium suppresses the protein expression levels of PI3K and p-Akt, and induce the protein expression of Bax in MC3T3-E1 cells[2]. Western Blot Analysis[2]
| ||||||||||||||||
体内研究 (In Vivo) | Disitertide (P144, Topical application, 300 μg/mL) diammonium may promote scar maturation and improvement of hypertrophic scar morphology features in an “in vivo” model in nude mice after two weeks of treatment[4].
| ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 1614.88 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C68H115N19O22S2 | ||||||||||||||||
Sequence Shortening | TSLDASIIWAMMQN | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Protect from light, stored under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 10 mg/mL(6.19 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在本网站选购。 |