Lenalidomide-C5-NH2 hydrochloride 是一种基于 Lenalidomide 的,可募集 CRBN 蛋白的 Cereblon 配体。Lenalidomide-C5-NH2 可通过 linker 与靶蛋白配体连接,形成 PROTAC 分子,比如 MDM2 的PROTAC 降解剂。
生物活性 | Lenalidomide-C5-NH2 hydrochloride is the Lenalidomide-basedCereblonligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to formPROTACs, such as MDM2PROTACdegrader[1][2]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |