| CAS NO: | 24425-56-7 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| Cas No. | 24425-56-7 |
| Canonical SMILES | CCCCCCSC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O |
| 分子式 | C16H29N3O6S |
| 分子量 | 391.5 |
| 溶解度 | DMSO: slightly soluble,DMSO:PBS (pH 7.2) (1:2): 0.3mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Hexylglutathione is a mitochondrial membrane-bound microsomal glutathione S-transferase 1 (mtMGST1) inhibitor (IC50 = 0.48 mM).1 It also inhibits the dopachrome tautomerase activity of macrophage migration inhibitory factor (MIF; IC50 = 3.3 mM).2 It has been used as an affinity chromatography ligand to purify glutathione S-transferase (GST) from sheep liver homogenate.3 |1. Ulziikhishig, E., Lee, K.K., Hossain, Q.S., et al. Inhibition of mitochondrial membrane bound-glutathione transferase by mitochondrial permeability transition inhibitors including cyclosporin A. Life Sci. 86(19-20), 726-732 (2010).|2. Swope, M.D., Sun, H.W., Klockow, B., et al. Macrophage migration inhibitory factor interactions with glutathione and S-hexylglutathione. J. Biol. Chem. 273(24), 14877-14884 (1998).|3. Reddy, C.C., Burgess, Z.Z., Gong, Z.Z., et al. Purification and characterization of the individual glutathione S-transferases from sheep liver. Arch. Biochem. Biophys. 224(1), 87-101 (1983). |
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