CAS NO: | 484049-04-9 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | DPH is a potent cell permeablec-Ablactivator, which displays potent enzymatic and cellular activity in stimulating c-Abl activation. | ||||||||||||||||
体外研究 (In Vitro) | DPH binds to the myristoyl binding site and prevents the formation of the bent conformation of the αI helix through steric hindrance, a mode of action distinct from the previously identified allosteric c-Abl inhibitor, GNF-2, that also binds to the myristoyl binding site. DPH represents the first cell-permeable, small-molecule tool compound for c-Abl activation[1]. | ||||||||||||||||
分子量 | 336.32 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C18H13FN4O2 | ||||||||||||||||
CAS 号 | 484049-04-9 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(297.34 mM;Need ultrasonic) 配制储备液
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