BTK-IN-16 是 Bruton’s tyrosine kinase (BTK) 的BTK wild type和C481S mutant的抑制剂,其IC50值分别为 5.1 和 4.1 μM。BTK-IN-16 可用于自身免疫疾病和慢性淋巴细胞白血病的研究。
生物活性 | BTK-IN-16 is a dual inhibitor ofBTKwild typeandC481S mutantof Bruton’s tyrosine kinase (BTK) withIC50s of 5.1 and 4.1 μM. BTK-IN-16 can be used for the research of autoimmune diseases and chronic lymphocytic leukemia[1]. |
IC50& Target | IC50: 5.1 μM (BTK wild type), 4.1 μM (C481S mutant)[1] |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |