Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 μM) with selectivity over L-type Ca2+ channels and GABAA receptors.
Cas No. | 50295-20-0 |
别名 | 利多卡因杂质K |
Canonical SMILES | CC1=C(NC(CN(C)CC)=O)C(C)=CC=C1.Cl |
分子式 | C13H20N2O•HCl |
分子量 | 256.8 |
溶解度 | DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 25 mg/mL,PBS (pH 7.2): 10 mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 µM) with selectivity over L-type Ca2+ channels and GABAA receptors. Lidocaine can also have pronociceptive effects by activating the transient receptor potential (TRP) channel TRPA1. N-(2,6-Dimethylphenyl)-2-(ethylmethylamino)acetamide is a lidocaine impurity. |