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Insulin(cattle)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:11070-73-8
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品名称
牛胰岛素
Insulin from bovine pancreas
产品介绍
Insulin cattle (Insulin from bovine pancreas) 是在胰腺 β 细胞中产生的两链多肽激素。Insulin cattle 在很多哺乳动物细胞培养体系中用作生长因子。
生物活性

Insulincattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells.Insulincattle has often been used as growth supplement in culturing cells.

体外研究
(In Vitro)

Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has often been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 μg/mL of medium.

分子量

5733.49

性状

Solid

Formula

C254H377N65O75S6

CAS 号

11070-73-8

Sequence

Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala. Gly-Ile-Val-Glu-Gln-Cys-Cys-Ala-Ser-Val-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn (Disulfide bridge: Cys7-Cys7', Cys19-Cys20', Cys6'

Sequence Shortening

FVNQHLCGSHLVEALYLVCGERGFFYTPKA. GIVEQCCASVCSLYQLENYCN (Disulfide bridge: Cys7-Cys7', Cys19-Cys20', Cys6'-Cys11')

中文名称

牛胰岛素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder-80°C2 years
-20°C1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O : 10 mg/mL(1.74 mM;ultrasonic and warming and adjust pH to 3 with HCl and heat to 60℃)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM0.1744 mL0.8721 mL1.7441 mL
5 mM---------
10 mM---------
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。