| CAS NO: | 78-41-1 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 生物活性 | Triparanol (MER-29) is a potentcholesterolbiosynthesisinhibitor blocking the 24-dehydrocholesterol reductase (24-DHCR). Triparanol can interfere with posttranslational modification ofHedgehogsignaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hh signaling. Triparanol suppresses human tumor growth[1][2]. | |||||||||
| 体外研究 (In Vitro) | Triparanol can block proliferation and induce apoptosis in multiple human cancer cells including lung, breast, liver, pancreatic, prostate cancer and melanoma cells, and growth inhibition can be rescued by exogenous addition of cholesterol[2]. | |||||||||
| 分子量 | 438.00 | |||||||||
| 性状 | Solid | |||||||||
| Formula | C27H32ClNO2 | |||||||||
| CAS 号 | 78-41-1 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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