CAS NO: | 1217510-38-7 |
包装 | 价格(元) |
500 μg | 电议 |
1mg | 电议 |
生物活性 | Itraconazole-d5 (R51211-d5) is the deuterium labeled Itraconazole. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally activeHedgehog(Hh) signaling pathwayantagonist with anIC50of ~800 nM. Itraconazole potently inhibits lanosterol14α-demethylase(cytochrome P450enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects[1][2][3]. |
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
分子量 | 710.66 |
Formula | C35H33D5Cl2N8O4 |
CAS 号 | 1217510-38-7 |
中文名称 | 伊曲康唑 d5 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |