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Iperoxo(iodide)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Iperoxo(iodide)图片
CAS NO:247079-84-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Iperoxo (iodide) 是毒蕈碱乙酰胆碱受体 (mAChR) 的强效超级激动剂。
Cas No.247079-84-1
Canonical SMILESC[N+](C)(C)CC#CCOC1=NOCC1.[I-]
分子式C10H17N2O2•I
分子量324.2
溶解度Water: 5 mg/ml (warmed)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Iperoxo is an agonist of muscarinic acetylcholine receptors. It stimulates [35S]GTPγS binding to CHO cell membranes expressing human M2 muscarinic receptors and cell membranes expressing M4 muscarinic receptors (EC50s = 2.12 and 8.47 nM, respectively). Iperoxo induces M1-dependent inhibition of the twitch response in electrically-stimulated isolated rabbit vas deferens (pD2 = 9.87) and M3-mediated contraction of isolated guinea pig ileum (pD2 = 9.78). In vivo, iperoxo reduces formalin-induced paw licking and acetic acid-induced writhing in mice (ED50s = 0.004 and 0.001 mg/kg, respectively).