您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Cremophor EL
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Cremophor EL
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:61791-12-6
包装与价格:
包装价格(元)
100 mL电议
200 mL电议
500 mL电议

产品名称
聚氧乙烯蓖麻油EL
产品介绍
Cremophor EL 是一种聚氧乙烯蓖麻油衍生物,是一种非离子表面活性剂。Cremophor EL 被广泛用于改善药物的溶解和输送。
生物活性

Cremophor EL, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL is widely employed to improve dissolution and delivery of drugs[1].

体外研究
(In Vitro)

Cremophor EL is a widely used excipient. In the first 10 h, Cremophor EL at 5 mg/mL increases the impedance, then decreases it, and after 20 h of treatment, epithelial cell death is detected. Cremophor EL decreases cell viability and increases cell toxicity more than RH40. Both epithelial viability and monolayer integrity are seriously impaired at 10 to 50 mg/mL concentrations of Cremophor EL at 24-h treatment. Cremophor EL also enhances cell detachment[1].

性状

Viscous liquid

CAS 号

61791-12-6

中文名称

聚氧乙烯蓖麻油EL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

溶解性数据
In Vitro: 

Ethanol : 50 mg/mL(Need ultrasonic)

H2O : 25 mg/mL(Need ultrasonic)