Liraglutide

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Liraglutide

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

204656-20-2

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议
10mg	电议
50mg	电议
100mg	电议

产品名称

利拉鲁肽

产品介绍

Liraglutide 是一种胰高血糖素样肽-1 (GLP-1) 受体激动剂，用于研究 2 型糖尿病。

生物活性

Liraglutide is aglucagon-like peptide-1(GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

IC₅₀& Target

GLP-1 receptor^[1]

体外研究
(In Vitro)

Liraglutide binds to the same receptors as does the endogenous metabolic hormone GLP-1. Liraglutide is an injectable drug for the treatment of type 2 diabetes, also can be used to treat obesity in adults with some related comorbidity. Liraglutide activated AMPK/SREBP1 pathway in oxLDL-stimulated Raw264.7 cells^[1].

Clinical Trial

分子量

3751.26

性状

Solid

Formula

C₁₇₂H₂₆₅N₄₃O₅₁

CAS 号

204656-20-2

Sequence Shortening

HAEGTFTSDVSSYL-{N6-[N-(1-oxohexadecyl)-L-γ-Etamyl]-Glu}-GQAAKEFIAWLVRGRG

中文名称

利拉鲁肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据

In Vitro:

H₂O : 9.09 mg/mL(2.42 mM;ultrasonic and adjust pH to 3 with HCl)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	0.2666 mL	1.3329 mL	2.6658 mL
5 mM	---	---	---
10 mM	---	---	---

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。