CAS NO: | 120788-07-0 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Sulopenem (CP-70429) is an orally active, parenteral penemantibioticwith broad-spectrum activities againstGram-positiveandGram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive againstPseudomonas aeruginosaandXanthomonas maltophilia[1][2][3]. | ||||||||||||||||
IC50& Target |
| ||||||||||||||||
体外研究 (In Vitro) | Sulopenem has the potential for uncomplicated and complicated urinary tract infections and intra-abdominal infections treatment, including multidrug-resistant (MDR) infections and infections attributable to quinolone-nonsusceptible and/or extended-spectrum β-lactamase (ESBL)-producing Gram-negative bacilli[1]. | ||||||||||||||||
体内研究 (In Vivo) | The protective effects of Sulopenem in murine experimental systemic infections are superior to those of Imipenem/Cilastatin. In murine experimental mixed infection withEscherichia coliandBacteroides fragilis, Sulopenem has lower ED50. In guinea pigs experimental lung infection withKlebsiella pneumoniae, Sulopenem is more effective than CZON or Cefotiam[3]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 349.45 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C12H15NO5S3 | ||||||||||||||||
CAS 号 | 120788-07-0 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
| ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 83.33 mg/mL(238.46 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在本网站选购。 |