CAS NO: | 96036-03-2 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Meropenem (SM 7338) is a carbapenemantibioticwith broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistantN. gonorrhoeae(MIC value of 0.02-0.06 mg/mL),H. influenzae(MIC value of 0.03-0.12 mg/mL), andH. ducreyi(MIC value of 0.015-0.12 mg/mL)[1][2]. | ||||||||
体外研究 (In Vitro) | Meropenem is intrinsically stable to dehydropeptidase-1 (DHP-1) degradation and Meropenem acts by inhibiting bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs). Meropenem possesses broad-spectrum in vitro activity, which includes activity against many Gram-positive, Gram-negative and anaerobic bacteria; Meropenem lacks activity against Enterococcus faecium, methicillin-resistant Staphylococcus aureus and Stenotrophomonas maltophilia[2]. | ||||||||
体内研究 (In Vivo) | Meropenem (60 mg/kg; intraperitoneal injection; once; SD rats) treatment significantly reduces the incidence of pancreatic infection[3].
| ||||||||
Clinical Trial | |||||||||
分子量 | 383.46 | ||||||||
Formula | C17H25N3O5S | ||||||||
CAS 号 | 96036-03-2 | ||||||||
中文名称 | 美罗培南;美洛培南 | ||||||||
结构分类 |
| ||||||||
来源 | aerobes and anaerobes | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |