CAS NO: | 390362-78-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | RHPS4 is a potenttelomeraseinhibitor (IC50= 0.33 μM). RHPS4 is a DNA damage inducer[1][2]. | ||||||||||||||||
IC50& Target | IC50: 0.33 μM (telomerase in the TRAP assay)[1]. | ||||||||||||||||
体外研究 (In Vitro) | RHPS4 could sensitize tumor cells to anticancer agents that act via disparate mechanisms[1]. Cell Proliferation Assay[1]
| ||||||||||||||||
体内研究 (In Vivo) | RHPS4 (15 mg/kg, iv, 15 days) treatment produces a marked inhibition of tumor weight (tumor weight inhibition [TWI] about 80%; P< 0.001) in a very short time, and this effect persists for at least 30 days. A complete tumor response is observed in 80% of mice, and 40% are cured[2].
| ||||||||||||||||
分子量 | 458.48 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C23H20F2N2O4S | ||||||||||||||||
CAS 号 | 390362-78-4 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 1 mg/mL(2.18 mM;ultrasonic and warming and heat to 60℃) H2O :< 0.1 mg/mL (ultrasonic;warming;heat to 60℃)(insoluble) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |