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(-)-Caryophyllene oxide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(-)-Caryophyllene oxide图片
CAS NO:1139-30-6
包装与价格：
包装价格(元)
100mg电议
1g电议

产品介绍
(-)-氧化石竹，从番荔枝中分离。
Cas No.1139-30-6
别名石竹素,(-)-Caryophyllene oxide
Canonical SMILESCC(C1)(C)[C@@]2([H])[C@@]1([H])C(CC[C@@H]3[C@](C)(O3)CC2)=C
分子式C15H24O
分子量220.4
溶解度DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(-)-Caryophyllene oxide is a bicyclic sesquiterpene and a metabolite of β-caryophyllene that has been found in C. sativa and has anticancer properties. Unlike β-caryophyllene, (-)-caryophyllene oxide does not bind to the cannabinoid (CB) receptor CB2 (Ki = >20 µM). It induces calcium currents in HL-60 cells expressing CB2 receptors but also does so in CB2-deficient cells. (-)-Caryophyllene oxide is cytotoxic to HepG2, AGS, HeLa, SNU-1 and SNU-16 cells (IC50s = 3.95, 12.6, 13.55, 16.79, and 27.39 µM, respectively). It is the volatile component of C. sativa sensed by narcotic detection dogs. Formulations containing (-)-caryophyllene have been used as flavoring agents.