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19(R)-HETE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
19(R)-HETE图片
CAS NO:115461-39-7
包装与价格:
包装价格(元)
25μg电议
50μg电议
100μg电议

产品介绍
Cas No.115461-39-7
Canonical SMILESCC(O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O
分子式C20H32O3
分子量320.5
溶解度DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 0.5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. However, 19(R)-HETE at 1 µM completely blocks 20-HETE-induced vasoconstriction of renal arterioles, whereas 19(S)-HETE remains inactive.