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12(R)-HETE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
12(R)-HETE图片
CAS NO:82337-46-0
包装与价格:
包装价格(元)
25μg电议
50μg电议
100μg电议

产品介绍
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid.
Cas No.82337-46-0
Canonical SMILESCCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(O)=O
分子式C20H32O3
分子量320.5
溶解度0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid . In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation. The activity of 12(R)-HETE in mammals is predominantly proinflammatory. 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.