您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Tulopafant
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Tulopafant
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tulopafant图片
CAS NO:116289-53-3
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
妥洛帕泛
RP 59227
产品介绍
Tulopafant 是血小板激活因子 (PAF) 拮抗剂。
生物活性

Tulopafant is a platelet activating factor (PAF) antagonist.

体外研究
(In Vitro)

Preincubation of neutrophils with Tulopafant (RP 59227) results in a concentration-dependent decrease in chemiluminescence produced by PAF primed cells[1].

体内研究
(In Vivo)

Tulopafant (RP 59227) effectively reduces myocardial infarct size and reduces the incidence of ischemia and reperfusion-induced arrhythmias in barbital-anesthetized dogs[1].Histological examination reveals marked diminution of both interstitial hemorrhage and deposition of platelet and granulocytes in capillaries of cardiac xenografts when recipient animals are pretreated with Tulopafant[2].

分子量

425.50

Formula

C25H19N3O2S

CAS 号

116289-53-3

中文名称

妥洛帕泛

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.