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Pravastatin-d3(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pravastatin-d3(sodium salt)图片
CAS NO:1329836-90-9
包装与价格:
包装价格(元)
500μg电议
1mg电议

产品介绍
普伐他汀-d3 (CS-514-d3) 钠盐是氘标记的普伐他汀钠盐。
Cas No.1329836-90-9
Canonical SMILESO=C(O[C@H]1C[C@H](O)C=C2[C@@]1([H])[C@@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@@H](C)C=C2)[C@@H](C([2H])([2H])[2H])CC.[Na+]
分子式C23H32D3O7• Na
分子量449.5
溶解度Methanol: Slightly soluble,Water: Slightly soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pravastatin-d3 is intended for use as an internal standard for the quantification of pravastatin by GC- or LC-MS. Pravastatin is a potent and competitive HMG-CoA reductase inhibitor (Ki = 2.3 nM for the active, open ring form of the molecule) that is a ring-hydroxylated metabolite of mevastatin . In vivo, pravastatin reduces total plasma cholesterol levels by 29% in dogs when administered at a dose of 20 mg/kg per day for five weeks. Formulations containing pravastatin have been used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease.