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Monactin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Monactin图片
CAS NO:7182-54-9
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Monactin 是一种大环四内酯类抗生素,是一种非选择性离子载体,用于单价阳离子,包括钾、钠和锂。
Cas No.7182-54-9
别名单活菌素
Canonical SMILESO=C(O[C@H](C)C[C@]1([H])O[C@@]([C@@H]2C)([H])CC1)[C@H](C)[C@@]3([H])CC[C@](C[C@H](C)OC([C@H]([C@@]4([H])O[C@](C[C@H](OC([C@H](C)[C@]5([H])O[C@](CC5)([H])C[C@H](C)OC2=O)=O)CC)([H])CC4)C)=O)([H])O3
分子式C41H66O12
分子量751
溶解度DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Monactin is a mactrotetralide antibiotic originally isolated from Streptomyces and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. It has low antimicrobial activity but is more active than its homolog nonactin . Monactin induces swelling of rat liver mitochondria in medium containing either potassium or sodium, stimulates respiration, and uncouples oxidative phosphorylation. It also inhibits Wnt signaling via inhibition of TCF-β-catenin transcriptional activity.