cis-6-Hexadecenoic Acid 是一种常见于皮肤和黏膜中的脂肪酸。
| Cas No. | 17004-51-2 |
| 别名 | C16:1(6Z), C16:1Δ6, C16:1ω10, Sapienic Acid |
| 化学名 | 6Z-hexadecenoic acid |
| Canonical SMILES | CCCCCCCCC/C=C\CCCCC(O)=O |
| 分子式 | C16H30O2 |
| 分子量 | 254.1 |
| 溶解度 | Chloroform: soluble,Ethanol: soluble,Ether: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | cis-6-Hexadecenoic acid is a monounsaturated fatty acid and is one of the primary fatty acids in human skin. cis-6-Hexadecenoic acid levels are increased in isolated sebum from the face and back of patients with acne. In contrast, levels are decreased in the non-lesional skin and isolated sebum of atopic dermatitis patients, which correlates with an increase in S. aureus in the sebum. It is active against S. aureus in vitro when used at a concentration of 5 µg/ml at pH 5.5. cis-6-Hexadecenoic acid disrupts membrane integrity, the proton motive force, increases membrane fluidity, and inhibits the electron transport chain in S. aureus. |
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