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SSTR5 antagonist 2 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SSTR5 antagonist 2 hydrochloride图片
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
SSTR5 antagonist 2 hydrochloride (compound 10) 是强效的、具有口服活性的生长激素抑制激素(受体)亚型 5 (SSTR5) 的选择性拮抗剂,有潜力用于 2 型糖尿病的研究。
生物活性

SSTR5antagonist 2 hydrochloride is a highly potent, oral active andselective somatostatin (receptor) subtype 5 (SSTR5)antagonist and has potential for the research of type 2 diabetes mellitus (T2DM)[1].

体内研究
(In Vivo)

SSTR5 antagonist 2 (compound 10) (10 mg/kg, orally) hydrochloride increases both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10 mg/kg[1].
SSTR5 antagonist 2 hydrochloride increases pancreatic insulin secretion as well as total and active GLP1 release, and demonstrates synergistic effects in combination with DPP4 inhibitors[1].

分子量

583.09

性状

Solid

Formula

C32H36ClFN2O5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO : 33.33 mg/mL(57.16 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM1.7150 mL8.5750 mL17.1500 mL
5 mM0.3430 mL1.7150 mL3.4300 mL
10 mM0.1715 mL0.8575 mL1.7150 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。