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Dolasetron(MDL-73147)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Dolasetron(MDL-73147)图片
CAS NO:115956-12-2
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议

产品介绍
Dolasetron (MDL-73147)(MDL-73147) 是一种血清素 5-HT3 受体拮抗剂，用于治疗化疗后的恶心和呕吐。
Cas No.115956-12-2
别名多拉司琼,MDL-73147
Canonical SMILESO=C(C1=CNC2=C1C=CC=C2)O[C@@H]3C[C@@](CC4C5)([H])[N@](CC4=O)[C@@]5([H])C3
分子式C19H20N2O3
分子量324.37
溶解度DMSO : ≥ 300 mg/mL (924.87 mM)
储存条件Store at 2-8℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

[1]. Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8. [2]. Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77.