Fidasimtamab (IBI-315; BH2950) 是一种重组人 IgG1 双特异性抗体，可同时靶向、结合并抑制HER2和PD-1及其下游信号通路，并将表达 PD-1 的 T 细胞与表达 HER2 的肿瘤细胞连接起来。Fidasimtamab 具有潜在的免疫抑制和抗肿瘤活性。
| 生物活性 | Fidasimtamab (IBI-315; BH2950) is a recombinant humanIgG1bispecific antibody that targets, binds and inhibits bothHER2andPD-1and their downstream signalling pathways, and linksPD-1expressing T cells to HER2 expressing tumour cells. Fidasimtamab has potential immunosuppressive and antitumor activity[1].
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| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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