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Acetyl β-Endorphin(human)(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Acetyl β-Endorphin(human)(trifluoroacetate salt)图片
包装:1mg
市场价:3009元

产品介绍
Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM).
分子式C160H253N39O47S•XCF3COOH
分子量3507
溶解度Water: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM). It induces chemotaxis of human monocytes in vitro when used at a concentration of 0.1 nM. In vivo, it reduces antinociception in mice induced by β-endorphin , morphine, [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin , and [D-Ala2, D-Leu5]-enkephalin (DADLE) in a tail-flick test (ED50s = 2.08, 33.11, 0.03, and 0.07 mol per animal, respectively).