包装: | 1mg |
市场价: | 3009元 |
分子式 | C160H253N39O47S•XCF3COOH |
分子量 | 3507 |
溶解度 | Water: 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM). It induces chemotaxis of human monocytes in vitro when used at a concentration of 0.1 nM. In vivo, it reduces antinociception in mice induced by β-endorphin , morphine, [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin , and [D-Ala2, D-Leu5]-enkephalin (DADLE) in a tail-flick test (ED50s = 2.08, 33.11, 0.03, and 0.07 mol per animal, respectively). |