4-Aminobenzoic Acid hydrazide 是一种不可逆的 MPO 髓过氧化物酶抑制剂，IC50 为 0.3 μM.
| Cas No. | 5351-17-7 |
| 别名 | 4-氨基苯甲酰肼,p-Aminobenzohydrazide; p-Aminobenzoic acid hydrazide |
| Canonical SMILES | NC1=CC=C(C(NN)=O)C=C1 |
| 分子式 | C7H9N3O |
| 分子量 | 151.2 |
| 溶解度 | DMF: 10 mg/ml,DMSO: 14 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Myeloperoxidase is an enzyme, produced by neutrophils and other myeloid cells, that is released upon degranulation. 4-Aminobenzoic acid hydrazide (4-ABAH) is an ABAH that specifically and irreversibly inhibits the peroxidation activity of myeloperoxidase (IC50 = 0.3 μM). This compound can be used with enzyme preparations, in cell cultures, and also in vivo. |
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