DBCO-PEG4-Val-Cit-PAB-MMAF

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	2244602-23-9
包装:	10mg
市场价:	10800元

产品介绍

DBCO-PEG4-Val-Cit-PAB-MMAF 由可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker (DBCO-PEG4-Val-Cit-PAB) 和 MMAF 组成，MMAF 是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂。DBCO-PEG4-Val-Cit-PAB-MMAF 可用于合成抗体偶联药物 (ADC)。

Cas No.	2244602-23-9
分子式	C₈₈H₁₂₆N₁₂O₂₀
分子量	1672.01
溶解度	DMSO : 250 mg/mL (149.52 mM; Need ultrasonic)
储存条件	Store at -20°C, stored under nitrogen
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)^[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].