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Hydroxygenkwanin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hydroxygenkwanin图片
CAS NO:20243-59-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Hydroxygenkwanin (7-O-Methylluteolin) 是一种天然的类黄酮化合物,是丁香达芙妮的主要成分之一。Hydroxygenkwanin 具有抗氧化,抗神经胶质瘤能力和抗癌作用。
Cas No.20243-59-8
别名羟基芫花素,7-O-Methylluteolin
Canonical SMILESO=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(OC)=CC(O)=C13
分子式C16H12O6
分子量300.26
溶解度Soluble in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].

Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner[1]. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway[2].

[1]. Wang Y, et al. Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro. Chem Biol Interact. 2013 Nov 25;206(2):346-55. [2]. Huang YC, et al. Anticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma. Front Oncol. 2019 Sep 18;9:911.