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Mitoquinol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Mitoquinol图片
CAS NO:845959-55-9
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Cas No.845959-55-9
化学名[10-(2,5-dihydroxy-3,4-dimethoxy-6-methylphenyl)decyl]triphenyl-phosphonium, monomethanesulfonate
Canonical SMILESOC1=C(CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C(C)=C(O)C(OC)=C1OC.O=S(C)([O-])=O
分子式C37H46O4P•CH3O3S
分子量680.8
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 0.3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mitoquinol is a ubiquinone derivative that specifically accumulates in mitochondria due to the covalent attachment of the cation triphenylphosphonium. It functions as an antioxidant, preventing lipid peroxidation-induced apoptosis and protecting mitochondria from oxidative damage.

Reference：
[1]. Kelso, G.F., Porteous, C.M., Coulter, C.V., et al. Selective targeting of a redox-active ubiquinone to mitochondria within cells. Antioxidant and antiapoptotic properties. J. Biol. Chem. 276(7), 4588-4596 (2001).
[2]. O'Malley, Y., Fink, B.D., Ross, N.C., et al. Reactive oxygen and targeted antioxidant administration in endothelial cell mitochondria. J. Biol. Chem. 281(52), 39766-39775 (2006).