CAS NO: | 57396-78-8 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
20mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Oroxin A is the major component of an ethanol-waterOroxylum indicum(L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partialPPARγagonist that can activatePPARγtranscriptional activation. Oroxin A activatesPPARγby docking into thePPARγprotein ligand-binding domain. Oroxin A also exhibits an inhibitory activity againstα-glucosidaseand an antioxidant capacity[1]. Oroxin A exerts anti-breastcancereffects by inducing ER stress-mediated senescence[2]. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Oroxin A (0.5- 100 μM; 24 hours) significantly increases the PPARγ transcription level and exhibits the strongest activation with 50 μM in HEK-293t cells[1]. | ||||||||||||||||
分子量 | 432.38 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C21H20O10 | ||||||||||||||||
CAS 号 | 57396-78-8 | ||||||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 125 mg/mL(289.10 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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