CAS NO: | 56-17-7 |
包装 | 价格(元) |
10 g | 电议 |
50 g | 电议 |
生物活性 | Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally activetransglutaminase (Tgase)inhibitor. Cystamine also has inhibition activity for caspase-3 with anIC50value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD)[1][2][3]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Cystamine (dihydrochloride) has inhibition activity for caspase-3 with an IC50value of 23.6 μM[1]. Western Blot Analysis[1]
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体内研究 (In Vivo) | Cystamine (dihydrochloride) (oral, i.p.; 112, 225 mg/kg) reduces Tgase activity and GGEL levels, lessens the behavioral and neuropathological severity, and extends survival in R6/2 transgenic HD mice[2].
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分子量 | 225.20 | ||||||||
性状 | Solid | ||||||||
Formula | C4H14Cl2N2S2 | ||||||||
CAS 号 | 56-17-7 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |