CAS NO: | 1807988-02-8 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Bictegravir sodium is a potent inhibitor ofHIV-1integrase, with anIC50of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity[1]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Bictegravir sodium potently inhibits HIV-1 replication in both MT-2 and MT-4 cells with EC50s of 1.5 and 2.4 nM, respectively, and selectivity indices (50% cytotoxic concentration [CC50]/EC50) of ~6,800 in MT-2 cells and ~1,500 in MT-4 cells[1]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 471.36 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C21H17F3N3NaO5 | ||||||||||||||||
CAS 号 | 1807988-02-8 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 16.67 mg/mL(35.37 mM;ultrasonic and warming and heat to 60℃) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |