HMG499是有效，选择性的HMG-CoA还原酶抑制剂，EC50为 0.41 μM。HMG499可预防他汀类药物诱导的HMGCR积聚，降低血清胆固醇水平，减少动脉粥样硬化。
| 生物活性 | HMG499 is a potent and selectiveHMG-CoA reductaseinhibitor with anIC50of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serumcholesterollevels and decrease atherosclerosis[1]. |
| IC50& Target | IC50: 0.41 μM (HMG-CoA reductase)[1] |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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