CAS NO: | 1802977-61-2 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potentlactate dehydrogenaseA (LDHA)inhibitor[1][2]. | ||||||||||||||||
IC50& Target | Lactate dehydrogenase A (LDHA)[1] | ||||||||||||||||
体外研究 (In Vitro) | Increased glucose consumption distinguishes cancer cells from normal cells and is known as the “Warburg effect” because of increased glycolysis. Lactate dehydrogenase A (LDHA) is a key glycolytic enzyme, a hallmark of aggressive cancers, and believed to be the major enzyme responsible for pyruvate-to-lactate conversion[1]. | ||||||||||||||||
分子量 | 499.04 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C25H23ClN2O3S2 | ||||||||||||||||
CAS 号 | 1802977-61-2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 20 mg/mL(40.08 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |