CAS NO: | 264206-85-1 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | GSK3987 is a panLXRα/βagonist withEC50s of 50 nM, 40 nM for LXRα-SRC1 and LXRβ-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellularcholesterolefflux and triglyceride accumulation[1]. | ||||||||||||||||
IC50& Target | EC50: 50 nM (LXRα); 40 nM (LXRβ)[1] | ||||||||||||||||
体外研究 (In Vitro) | GSK3987 (compound 4) shows activity with EC50s of 0.08 μM, 50 nM, 40 nM for ABCA1, LXRα-SRC1, LXRβ-SRC1, respectively[1]. RT-PCR[1]
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分子量 | 384.43 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C24H20N2O3 | ||||||||||||||||
CAS 号 | 264206-85-1 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(260.13 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |