Stigmasterol

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Stigmasterol

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

83-48-7

包装与价格：

包装	价格(元)
100mg	电议
200mg	电议
500mg	电议

产品名称

豆甾醇
Stigmasterin

产品介绍

Stigmasterol (Stigmasterin) 是一种植物性甾醇，不仅具有降低胆固醇的活性，并且在风湿性疾病的研究中被评价为抗硬化因子。

生物活性

Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.

IC₅₀& Target

Human Endogenous Metabolite

体外研究
(In Vitro)

Preincubation of Stigmasterol to IL-1beta-treated cells shows significant reduction of MMP-3 mRNA in human and mouse, MMP-3 protein in mouse, MMP-13 mRNA in mouse and human, ADAMTS-4 mRNA in human, PGE2 protein in human and mouse. Stigmasterol is also capable of counteracting the IL-1beta-induced NF-κB pathway^[1].

分子量

412.69

性状

Solid

Formula

C₂₉H₄₈O

CAS 号

83-48-7

中文名称

豆甾醇

结构分类

Steroids

来源

Plants
Amaranthaceae
Achyranthes bidentata

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

Acetone : 6.67 mg/mL(16.16 mM;Need ultrasonic)

DMF : 1 mg/mL(2.42 mM;ultrasonic and warming and heat to 60℃)

H₂O :< 0.1 mg/mL(insoluble)

1M NaOH :< 1 mg/mL(insoluble)

Ethanol :< 1 mg/mL(insoluble)

DMSO :< 1 mg/mL(insoluble or slightly soluble)

MEOH :< 1 mg/mL(insoluble)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.4231 mL	12.1156 mL	24.2313 mL
5 mM	0.4846 mL	2.4231 mL	4.8463 mL
10 mM	0.2423 mL	1.2116 mL	2.4231 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。